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HORIBA - Developments in Biopharma processes using Optical Spectroscopy

IBioIC is delighted to host this in person event with HORIBA.

Talks will be given on monitoring, yield and process improvements in biomanufacturing using absorbance and spectroscopy.

Agenda

09:30 Registration (refreshments included)

10:00 Welcome and housekeeping - Neil Renault, IBioIC

10:05 Introduction to HORIBA – Andy Keating, Marketing Development Manager

10:10 Dr Gioriga Marucci, Regional Product Manager for Fluorescence Spectroscopy

Talk title: A-TEEM (Absorbance – Transmission Excitation Emission Matrix) – the future of PAT and QC/QA in Biopharmaceutical Production

10:30 Q&A

10:40 Refreshment break

10:55 Dr Adam Holland, Senior Product Manager, Raman and micro-PL Spectroscopy

Talk title -Biopharmaceutical Material and Process improvements guided by Raman spectroscopy

11:15 Q&A

11:25. Closing Remarks – Neil Renault


Speakers

Speaker 1 : Dr Gioriga Marucci, Regional Product Manager for Fluorescence Spectroscopy

Title: A-TEEM (Absorbance – Transmission Excitation Emission Matrix) – the future of PAT and QC/QA in Biopharmaceutical Production

Abstract

Absorbance – Transmission Excitation Emission Matrix (A-TEEM) spectroscopy and multivariate analysis facilitate making decisions with fast and accurate monitoring of the manufacturing process of biopharmaceutical therapies and vaccines.

Biography

As fluorescence spectroscopy specialist, Giorgia is responsible for supporting HORIBA’s customers with their advanced use of its fluorescence portfolio. She completed her PhD in Applied Sciences at Northumbria University in Newcastle upon Tyne, focusing on the development of spectroscopic and imaging techniques to study historical and art objects. Upon completion of her PhD, she moved into the photonics industry, gaining experience, and understanding in a broad range of spectroscopy instrumentation and application fields, ranging from life science to material science.

Speaker 2:

Dr Adam Holland, Senior Product Manager, Raman and micro-PL Spectroscopy

Title: Biopharmaceutical Material and Process improvements guided by Raman spectroscopy

Abstract

Over the last three decades Raman spectroscopy has seen increasing adoption throughout the pharmaceutical industry and is now extensively used all levels of the pharmaceutical process. Raman spectroscopy is used from drug discovery and IP, through formulation, all the way to process monitoring and quality control, and even for counterfeit detection. The drive towards Process Analytical Technology (PAT) has led towards Raman becoming an essential tool for the pharmaceutical industry. The recent industry shift to biotherapeutic drug development has introduced many new challenges. Raman spectroscopy has provided information to overcome a myriad of these challenges.

This talk will introduce Raman spectroscopy and its applicability to biopharmaceutics, followed by three specific examples, protein analysis, virus detection using surface enhanced Raman spectroscopy (SERS) and a study of biotherapeutic stability.

Biography

Dr Holland has over 30 years experience of optical spectroscopy, beginning with a doctorate from the University of Oxford. Since joining HORIBA he initially worked as an applications engineer on a variety of optical spectroscopy techniques, from a novel method of fluorescence quantum yield measurement through display characterisation for the entertainment industry to Raman imaging for amongst others pharmaceutical formulation and counterfeit analysis. Today he provides detailed measurement advice to HORIBA’s customers and develops new applications methods for a wide range of markets based on Raman nanoRaman and micro-photoluminescence technologies.

Location

The Technology and Innovation Centre (Level 9) University of Strathclyde 99 George Street Glasgow G1 1RD

Earlier Event: 19 April
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Later Event: 10 May
Chem UK 2023