INTRODUCTION TO DOWNSTREAM PROCESSING

Based in FlexBio our pilot-scale facility in Edinburgh, this course is aimed at scientists, engineers, suppliers, postgraduate students and postdocs who want to learn more about downstream bioprocessing specific to the biotech sector. This classroom and lab based course covers methods for industrial downstream processing and the factors to be considered when choosing which one is best for your process.

Course content typically covers:

  • Solids separation - Disc-stack centrifuge operation, clean in place (CIP) and dismantle
  • Product isolation - homogenisation of cell solids
  • Filtration - Cross-flow filtration of supernatant using Sartorius Sartoflow
  • Purification - Isolation of target proteins using AKTA chromatography
  • Overview of other techniques - Formulation and fill, freezing drying

Find out when this course will next run and book a place on our Scale-Up Centres website.